Determination of the Kinetic Behavior of Diclofenac in Aqueous Solution by UV Light Radiation

Abstract

Diclofenac (DCF) is one of the most widely used non-steroidal anti-inflammatory drugs worldwide, and several studies have reported adverse effects on the environment, in plants and animals; so, it is classified as an emerging pollutant. There are several alternatives for its removal; however, it is necessary to study the way in which the DCF is degrading to offer more effective removal techniques, since the traditional ones such as chlorination, activated sludge, and biofiltration offer low removal efficiency (20–40%). This work analyzes the kinetic behavior of the photodegradation of DCF and the thermodynamic parameters of the reaction under UV-C-type light radiation. The results obtained indicate that it presents a first-order kinetic promoted by the increase of the temperature. Also, within the evaluated interval (273 to 308 K), the values of the kinetic coefficient (k) range between 0.05 and 0.20 min−1 and the half-life ranges from 3 to 9 min. The reaction is exothermic and spontaneous and gives way to the formation of approximately 6 byproducts, being two with the reatest presence and stability. This suggests that its decomposition route occurs through the dechlorination of the molecule and originate compounds known as carbazoles that have been detected in revious works. It was also found that this mixture of byproducts remained after the degradation of the drug, which is released to the environment, so it is necessary to extend a study on its properties and its possible environmental impact.