Resumen:
This study aimed to detect the quantitative trait loci (QTL) which affecting the growth traits in some parts of
chromosomes 1 of Sanjabi lambs. The study population consisted of six groups of fathers which had an average of
39.17 lambs. Initially, the fathers were genotyped for eight microsatellite markers on chromosome 1, and the
offspring of the heterozygote fathers were genotyped. The quantitative traits were the body’s weight at birth, 3,
6, 9, and 12 months, which were corrected for the fixed effects of year of birth, sex, and birth type. QTL search
was performed by interval mapping based on a regression model for each cM (Centimorgan) of the chromosomes.
In total, one QTL in the 235 cM of chromosome 1 was identified from the beginning of the chromosome in
associate with weaning weight. The sire substitution effect for both families was 2.14 kg. The confidence interval
estimation of the detected QTL that was estimated using the Bootstrap method was 225–238 cM of chromosome
1. This QTL was determined between the MCM137 and MCM130 markers and at a distance of about 9 cM from
the MCM137 marker. If this QTL was approved in the next research, it can be used in Marker-assisted selection
programs. In this case, more accuracy should be achieved for the evaluation of superior animals.
Descripción:
Sheep is one of the most economically important livestock used as a source of meat, milk, wool, and skin for human society. Raising sheep in Iran due to the interest of people for using sheep meat instead of cattle or chicken meat and sacrificing in religious ceremonies is very important. Determine the genetic background of quantitative traits is very important to increase the production of domestic animals (Gebreselassie et al., 2020). Sanjabi sheep is one of the most important breeds in Iran, which produce good quality of meat and wool. This animal is highly resistant to local diseases and has a good daily weight gain during fattening (220 g/day) (Mohammadi et al., 2010). Bodyweight traits at different ages are among the most important economic traits of sheep, which is directly related to the amount of production and profit of the farmer.
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