Resumen:
Depression is currently one of the most common mental disorders worldwide. Although there are valuable
and effective psychotherapeutic models for its treatment, most focus on reducing symptoms and illness. In contrast, the
Positive Psychology approach promotes well-being by developing and implementing strategies, called Positive Clinical
Interventions (PCIs) that aim to enhance the development and satisfaction of individuals to promote health, quality
of life, and excellence. Methods: This review aimed to synthesize the available evidence on the effectiveness of PCIs
according to the type and therapeutic model implemented to increase well-being and reduce depressive symptoms in
adults, as well as to identify their value and balance between innovation and effectiveness. We searched PubMed, PsycINFO
and SCOPUS, followed the PRISMA guidelines and assessed the methodological quality of the studies. Our review
has been registered in PROSPERO (CRD42024551678). Results: The methodological quality of the studies was assessed
using the Effective Public Health Practice Project (EPHPP), which allowed six studies out of 178 to be included in the
systematic review. Second and third-generation treatment models were identified. All studies reported an improvement
in depressive symptoms and an increase in well-being immediately after the intervention and up to six months later.
Conclusions: According to the results, PCIs are effective, but studies with more rigorous protocols and methods are
needed to avoid bias.