Resumen:
Mexico is a diverse country in terms of culture and natural environments. For this reason, the delimitation of homogeneous basins with similar environmental, social, and economic attributes is important in order to facilitate the elaboration of high-impact regional development strategies. However, this represents an ongoing challenge due to the complexity of the interactions that occur within socio-ecological systems at a regional scale. In the present study, the main objective was to identify the interrelationships among different aspects of the socio-ecological system located within basins, with the goal of utilizing this information to promote the region-specific sustainable development of an Integrated Water Resources Management (IWRM). Therefore, in this study, environmental, social, economic, and institutional variables, relevant to water management and with thecapacitytobeexpressedspatially,wereutilizedtoidentifyregionswithsimilarcharacteristicsand to regionalize the urban sub-basins of Mexico based on a principal component analysis (PCA) and the k-medoids clustering algorithm. The identification of the most adequate number of regions at the national level was determined by the silhouette method. As a result, five distinct regions for Mexico were generated, which forms the first step in the design of integrated water resources management strategies for these regions.