Resumen:
The aim of this study is to investigate the biopotency of methanolic extracts of Vitex mollis, Psidium guajava,
Dalbergia retusa, and Crescential alata leaves against various staphylococcal strains isolated from cattle and
rabbits. Methicillin-resistant S. aureus strains were isolated from cattle, while other strains were isolated from
rabbits using standard methodology. The total phytochemical phenolic and saponins contents were obtained
being the main groups of the antinutritional factors. The antimicrobial activity of the extracts against the
standard culture of S. aureus (control) and S. aureus isolated from cattle and rabbits were investigated comparatively
relative to that of oxacillin. It was found that both the control S. aureus and the isolated S. aureus are
susceptible to all the four plant extracts, and sensitive to oxacillin. Of all the S. aureus including the control,
MRSA2 is the most susceptible to all the extracts at 1000 μg/mL, except that of V. mollis where it is the least
susceptible. Among all the plant extracts, P. guajava is the most active against MRSA2 and SOSA2. Therefore, the
isolates from cattle (MRSA1 and MRSA2) are more susceptible to all the plant extracts than the isolates from
rabbits. Among all the rabbit isolates, CoNS3 is the least susceptible to the extracts. Since all the plant extracts
exhibit remarkable inhibitory activities against all the S. aureus strains, they are promising towards the production
of therapeutic drugs.